Edit Mode,"Toggling to edit mode allows for editing, creation, and deletion of ROIs.  In addition, this is the mode in which ROI tagging and labeling takes place."
Align Mode,"Toggling to align mode allows for the transformation of ROI Lists from separate imaging sessions into a common space, allowing for simultaneous visualization of independently drawn sets.  In this view, ROI objects can be deleted (as in the case of singleton ROIs that were perhaps a false positive), and ROIs can be registered across days."