Metadata-Version: 1.2
Name: pharmpy-core
Version: 0.10.0
Summary: Pharmacometric modelling
Home-page: https://pharmpy.github.io
Author: Rikard Nordgren
Author-email: rikard.nordgren@farmbio.uu.se
License: GNU Lesser General Public License v3 (LGPLv3)
Project-URL: Bug Tracker, https://github.com/pharmpy/pharmpy/issues
Project-URL: Source Code, https://github.com/pharmpy/pharmpy
Description: Pharmpy is a library for pharmacometrics. It can be used as a regular python package, in R via reticulate or via its built in command line interface.
        
        Pharmpy is architectured to be able to handle different types of model formats and data formats and exposes a model agnostic API.
        
        Current features:
        
        * Parsing of many parts of a NONMEM model file
        * Parsing of NONMEM result files
        * CLI supporting dataset filtering, resampling, anonymization and viewing
        
        Pharmpy is developed by the Uppsala University Pharmacometrics group.
        
        0.10.0 (2020-11-16)
        -------------------
        
        * modeling.create_rv_block 
        * modeling.michaelis_menten_elimination
        * modeling.set_transit_compartments
        * First version of modelfit method
        * Add first version of bootstrap method
        * Add parameter estimates histograms to bootstrap report
        * Add automatic update of $SIZES PD when writing/updating NONMEM model
        * Additions to QAResults
        * NMTRanParseError replaced with ModelSyntaxError
        * Multiple bugfixes to frem and scm result calculations
        
        0.9.0 (2020-10-26)
        ------------------
        
        * Add error_model function to the modeling module
        * Added more standard models for modeling.add_etas
        * Improve BootstrapResults
        * Add plots to bootstrap
        * Add support for the PHARMPYCONFIGPATH environment variable
        * Add QAResults and LinearizeResults classes
        * Bugfixes for some Windows specific issues
        
        0.8.0 (2020-10-08)
        ------------------
        
        * Add basic modeling functions to the modeling module
        * modeling.add_etas
        * Improved bootstrap results generation and additional plots
        * Bugfix: Labelled OMEGAS could sometimes get wrong symbol names
        
        0.7.0 (2020-09-28)
        ------------------
        
        * Add method reset_indices in Results to flatten multiindices. Useful from R. 
        * absorption_rate can also set sequential zero first absorption
        * New functionsadd_lag_time and remove_lag_time in modeling
        * Add basic functions fix/unfix_parameter, update_source and read_model to modeling API
        * Updated reading of NONMEM results
        * Bugfixes in add_covariate_effects and absorption_rate
        * Fix crash in FREM results if no log option could be found in meta.yaml
        
        0.6.0 (2020-09-18)
        ------------------
        
        * Add eta transformations: boxcox, t-dist and John Draper 
        * Add results cdd and scm to CLI
        * Add different views for scm results
        * Add support for taking parameter names from comment in NONMEM model
        * Remove assumptions for symbols
        * Add modeling.absorption_rate to set 0th or first order absorption
        * Add update of $TABLE numbers
        
        0.5.0 (2020-09-04)
        ------------------
        
        * Many bugfixes and improvements to NONMEM code record parser
        * Add calculation of symbolic and numeric eta and eps gradients, population and individulal prediction and wres for PRED models
        * Add option to use comments in NONMEM parameter records as names for parameters
        * Reading of ODE systems from NONMEM non-$DES models
        * Calculation of compartmental matrix and ODE system
        * New module 'modeling'
        * Function in modeling and CLI to change ADVAN implicit compartmental models to explicit $DES
        * Function in modeling and CLI to add covariate effects
        * Functions for reading cdd and scm results from PsN runs
        * Many API updates
        * Extended CLI documentation
        
        0.4.0 (2020-07-24)
        ------------------
        
        * Add categorical covariates to covariate effects plot in FREM
        * Better support for reading NONMEM code statements (PK and PRED)
        * Support for updating NONMEM code statements (PK and PRED)
        * Bugfixes for CLI
        
        
        0.3.0 (2020-06-16)
        ------------------
        
        * New CLI command 'data append'
        * Parameter names is now the index in Parameters.summary()
        * FREM postprocessing
        * Standardized results.yaml and results.csv
        
        0.2.0 (2020-03-27)
        ------------------
        
        First release
        
        
        0.1.0 (2018-07-22)
        ------------------
        
        Initial library development/testing directory structure.
        
Keywords: pharmacometrics
Platform: UNKNOWN
Classifier: Development Status :: 4 - Beta
Classifier: Intended Audience :: Science/Research
Classifier: Intended Audience :: Developers
Classifier: License :: OSI Approved :: GNU Lesser General Public License v3 (LGPLv3)
Classifier: Operating System :: POSIX
Classifier: Operating System :: MacOS
Classifier: Operating System :: Unix
Classifier: Operating System :: Microsoft :: Windows
Classifier: Programming Language :: Python
Classifier: Programming Language :: Python :: 3 :: Only
Classifier: Programming Language :: Python :: 3.6
Classifier: Programming Language :: Python :: 3.7
Classifier: Programming Language :: Python :: 3.8
Classifier: Programming Language :: Python :: Implementation :: CPython
Classifier: Topic :: Scientific/Engineering
Requires-Python: >=3.6
